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Antibody Titration

Antibody Titration

Antibody titration assays are required in several critical medical scenarios to make important therapeutic decisions. On the other hand, antibody titration testing are tedious, time-consuming and resource-intensive procedures, so the fact that they can be performed automatically facilitates their use and expands the responsiveness and efficiency of the immunohematology laboratory. 

Erytra and Erytra Eflexis facilitate fully automated titration procedures for both regular and irregular antibodies, IgG or IgM, from 1:1 up to 1:2048 dilution. Our systems ensure full traceability and delivers fast and reliable results.

Our solutions

Find the right method to perform this assay

Gel card technology

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Reagents for this assay

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Conventional techniques

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Gel card technology

DG Gel cards organize your antibody titration and meet the specific needs of your immunohematology laboratory

DG Gel cards are the original 8-column column agglutination technology (CAT). DG Gel cards paired with high-quality reagents facilitate efficient antibody titration in any workflow. Screen blood quickly and safely for antibodies, common and rare and in all testing configurations.

DG Gel Cards for this assay

210344
DG Gel Anti-IgG

DG Gel Anti-IgG gives you antibody investigation including titration testing in monospecific coombs media that fits your needs.

Configuration:
IgG | IgG | IgG | IgG | IgG | IgG | IgG | IgG

210342
DG Gel Coombs

With DG Gel Coombs, flexible testing is simple with one versatile card for antibody investigation techniques such as titration in polyspecific coombs media.

Configuration:
AHG | AHG | AHG | AHG | AHG | AHG | AHG | AHG

210343
DG Gel Neutral

Obtain loads of information using the 8 buffered gel media to perform saline and enzymatic techniques to investigate unexpected antibodies like titration studies.

Configuration:
N | N | N | N | N | N | N | N

Reagents for this assay

Our systems are designed to meet the specific needs of your immunohematology laboratory. Erytra, Erytra Eflexis and DG Reader Net, using Reagent Red Blood Cells from our portfolio, allow fully automated titration testing, ensuring accuracy, standardization and reliability.

Any 0.8% Reagent Red Blood cell from our portfolio can be used for titration with DG Gel cards. To see the available list, go to the Antibody Screening and Antibody Identification pages of this website.

In addition, no need of additional solutions or disposables, reducing plastic waste generation. Only our universal diluent is needed for both manual and automated methods, as well as some complementary reagents:

Name
Code

210354

Description

Reagent used for suspending red blood cells and diluting plasma or serum samples

Code

213679

Description

Solutions used for the washing of the Grifols instruments' fluidic system

Code

213678

Description

Solutions used for the washing of the Grifols instruments' fluidic system

Name Code Description

DG Gel Sol

210354

Reagent used for suspending red blood cells and diluting plasma or serum samples

DG Fluid A

213679

Solutions used for the washing of the Grifols instruments' fluidic system

DG Fluid B

213678

Solutions used for the washing of the Grifols instruments' fluidic system

Conventional techniques

Conventional reagents that are a proven and reliable solution for every type of lab

Whether you are utilizing conventional tube reagents for most of your testing or for resolving problematic cases, it is important to have a wide range of reagent red blood cells and antisera to meet your needs. 

Simplifying antibody titration procedures for conventional serology is easy with our range of reagents. 

Reagents for this assay:

Any 3% Reagent Red Blood cell from our portfolio can be used for titration. To see the available list, go to the Antibody Screening and Antibody Identification pages of this website.

Name
Code

210935

Description

Polyspecific Coombs reagent to detect immunoglobulin and /or complement bound to red blood cells in direct and indirect antiglobulin tests

Code

213559

Description

Monospecific Coombs reagent for indirect antiglobulin tests to differentiate between IgG and complement sensitization

Name Code Description

Anti-Human Globulin Polyspecific

210935

Polyspecific Coombs reagent to detect immunoglobulin and /or complement bound to red blood cells in direct and indirect antiglobulin tests

Anti-IgG

213559

Monospecific Coombs reagent for indirect antiglobulin tests to differentiate between IgG and complement sensitization

Quality Controls and Complementary Solutions for this assay:

Name
Code

213394

Description

Positive control for antiglobulin tests based on red cells sensitized with humnan IgG antibodies

Code

213422

Description

Complementary solution to enhance the antigen-antibody reaction of compatibility testing, antibody screening, identification and titration

Code

213573

Description

Complementary solution to enhance the antigen-antibody reaction of compatibility testing, antibody screening, identification and titration

Code

213577

Description

Low Ionic Strength Solution used to enhance antigen-antibody reactions in tube procedures such as compatibility testing, antibody screening, identification and titration

Name Code Description

Coombs Control

213394

Positive control for antiglobulin tests based on red cells sensitized with humnan IgG antibodies

Specific Albumin 22%

213422

Complementary solution to enhance the antigen-antibody reaction of compatibility testing, antibody screening, identification and titration

Specific Albumin 30%

213573

Complementary solution to enhance the antigen-antibody reaction of compatibility testing, antibody screening, identification and titration

ENLISST-II

213577

Low Ionic Strength Solution used to enhance antigen-antibody reactions in tube procedures such as compatibility testing, antibody screening, identification and titration

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