ID CORE XT
Product Detail Specification
Assay type Blood group genotyping assay
Detection & determination Detects 29 polymorphisms determining 37 red blood cell antigens
Main applications
  • Determining the presence/absence of blood groups in chronically and recently transfused patients
  • Screening routine donors
  • Selecting compatible donors
Blood Groups Alleles Assayed Phenotypes (Antigens)
RhCE RHCE*ce; RHCE*Ce, RHCE*cE;
RHCE*CE, RHCE*CeCW, RHCE*ceCW,
RHCE*CECW, RHCE*ceAR, RHCE*CeFV,
RHCE*CeVG, RHCE*cEFM, RHCE*ce[712G],
RHCE*Ce[733G], RHCE*ce[733G], RHCE*ce[733G,1006T],
RHCE*CE-D[5,7]-CE, RHCE*cE[712G,733G],
RHD*r's-RHCE*ce[733G,1006T]
C (RH2), E (RH3), c (RH4), e (RH5), CW (RH8), V (RH10), hrS (RH19), VS (RH20) , hrB (RH31)
Kell KEL*K_KPB_JSB, KEL*k_KPB_JSB, KEL*k_KPA_JSB, KEL*k_KPB_JSA K (KEL1), k (KEL2), Kpa (KEL3), Kpb (KEL4), Jsa (KEL6), Jsb (KEL7)
Kidd JK*A, JK*B, JK*B_null(871C), JK*A_null(IVSS-1a), JK*B_null(IVS5-1a) Jka (JK1), Jkb (JK2)
Duffy FY*A; FY*B, FY*A_GATA, FY*A[265T], FY*B_GATA, FY*B[265T]_FY*X Fya (FY1), Fyb (FY2)
MNS GYPA*M, GYPA*N, GYPB*s, GYPB*S, GYPB*S_null(230T), GYPB*S_null(IVS5+5t), GYP.Mur, GYPB*deletion M (MNS1), N (MNS2), S (MNS3), s (MNS4), U (MNS5), Mia (MNS7)
Diego DI*A, DI*B Dia (DI1), Dib (DI2)
Dombrock DO*A, DO*B, DO*B_HY, DO*A_JO Doa (DO1), Dob (DO2), Hy (DO4), Joa (DO5)
Colton CO*A, CO*B Coa (CO1), Cob (CO2)
Cartwright YT*A, YT*B Yta (YT1), Ytb (YT2)
Lutheran LU*A, LU*B Lua (LU1), Lub (LU2)

Notes:
One kit contains 48 tests. ID CORE XT is manufactured by Progenika, a Grifols company.


ID HPA XT
Product Detail Specification
Assay type Human platelet antigen (HPA) genotyping assay
Detection & determination Detects 13 polymorphisms determining 12 HPA systems
Main applications
  • Determining the presence/absence of platelet antigens in both patients and donors
  • Performing large-scale donor typing for provision of antigen-negative platelets
  • Helping to select compatible platelet donors for refractory or alloimmunized patients and complementing clinical history of alloimmune platelet disorders, such as foetal and neonatal alloimmune thrombocytopenia (FNAIT)
  • Post-transfusion purpura and platelet transfusion refractoriness
Human Platelet Antigens Alleles Assayed Phenotypes (Antigens)
HPA-1 HPA1a, HPA1b HPA-1a, HPA-1b
HPA-2 HPA2a, HPA2b HPA-2a, HPA-2b
HPA-3 HPA3a, HPA3b HPA-3a, HPA-3b
HPA-4 HPA4a, HPA4b HPA-4a, HPA-4b
HPA-5 HPA5a, HPA5b HPA-5a, HPA-5b
HPA-6 HPA6a, HPA6b HPA-6bw
HPA-7 HPA7a, HPA7b HPA-7bw
HPA-8 HPA8a, HPA8b HPA-8bw
HPA-9 HPA9a, HPA9b HPA-9bw
HPA-10 HPA10a, HPA10b HPA-10bw
HPA-11 HPA11a, HPA11b HPA-11bw
HPA-15 HPA15a, HPA15b HPA-15a, HPA-15b

Notes:
One kit contains 48 tests. ID HPA XT is manufactured by Progenika, a Grifols company.


ID RHD XT
Product Detail Specification
Assay type Blood group genotyping assay
Detection & determination Detects 6 polymorphisms determining 6 RHD variants and HPA-1
Main applications
  • Determining the presence/absence of weak D subtyping to rationalize the use of D negative blood units
  • Determining the presence/absence of weak D pregnant women subtyping to avoid unnecessary RhIG injections
  • Confirmation of D negative donors
Blood Groups Alleles Assayed Phenotypes (Antigens)
Rh RHD* weak D type 1 Weak D Type 1
Rh RHD* weak D type 2 Weak D Type 2
Rh RHD* weak D type 3 Weak D Type 3
Rh RHD* pseudogene D-
Rh RHD* DIIIa-CE(3-7)-D D-
Rh RHD deletion D-
HPA-1 HPA1a, HPA1b HPA-1a, HPA-1b

Notes:
One kit contains 24 tests. ID RHD XT is manufactured by Progenika, a Grifols company.

ID CORE CONTROL
Product Detail Specification
Assay type Positive control for ID CORE XT
Detection & determination 2 clones including testing for all allele A and B of all polymorphisms tested in ID CORE XT
Main benefits
  • Standarization of the system quality control processes
  • Practical: already commercially available, the laboratory does not have to produce their own controls
  • Allows control of all tested alleles

Note:
One kit contains 25 tests. ID CORE CONTROL is manufactured by Progenika, a Grifols company.

BIDS XT
Product Detail Specification
Description Software solution to accompany ID CORE XT and ID HPA XT kits
Main applications
  • Assisting with the genotyping process including plate configuration, kit and enzyme lot and registration functions to help users trace sample reagents and results
  • Creating and storing results in a database that can perform multiple-searches and then export results in several formats including LIS

This information is intended for physicians and healthcare professionals only.

ID CORE XT, ID HPA XT, ID RHD XT, BIDS XT, and ID CORE CONTROL comply with the Directive 98/79/EC of the European Parliament and of the Council on in vitro diagnostic medical devices. CE mark certification.

ID CORE XT, ID CORE CONTROL, and BIDS XT are sold in the US as IVD (FDA).

ID HPA XT and ID RHD XT are sold in the US for research use only (RUO). Not for use in diagnostic procedures.

Product registration and availability vary by country. Ask your local Grifols representative for more information or contact us here.